Endocrine Abstracts

Leptin is best known as an appetite and metabolic rate modulator secreted from fat, but it also has a range of other functions including modulation in reproductive physiology. To date, most studies examining the role of leptin in male reproduction have focussed on individual tissues, often in vitro. In the current report, a bolus physiological dose of iodinated leptin was administered intravenously to male mice to and samples collected over a one hour time course to d...

Objective: The 2016 ATA RR assessment recommendations for patients with DTC were based on retrospective studies. We present the first outcomes of a prospective assessment of thyroid cancer management according to the ATA RR stratification.Methods: Using the Calgary prospective thyroid cancer database, we identified 612 patients with differentiated thyroid cancer (DTC) treated at our centre between April 2017 and December 2021. Each case was reviewed by t...